“Appa got me the Cheetos”, said the daughter sounding gleeful over dinner.
Cheetos, I had explained to her that morning, was full of food coloring, and therefore not a good idea.
“You went and asked him for that after everything I explained to you this morning? Carcinogens. You know what? I think you should look up Mammoth DNA sequences and compare and contrast it with the genome of an Asian elephant.”
“That is the world’s worst punishment ever!” she said pulling an impressive teenage affront with ease. “I don’t think anyone has been given that.”
“Well..there are several reasons you are being given that, “, I said. “One: I am reading the book that is all about resurrecting the woolly mammoth by impregnating an Asian elephant with mammoth genes. Two: Did you know that the elephant, that large an animal as it is, does not suffer from cancer? Maybe there is something in it’s genetic makeup that prevents malfunctions during cell reproduction.” I said giving her my Idiot’s Guide to Genetics lecture.
It’s true. I had just finished reading the book called “Woolly – Bringing a woolly mammoth back to life” by Ben Mersich. For someone who does not know the first thing about genetics and genome sequencing and such, this is a good book to read. It is written like a fast paced novel, moving between the lives of reclusive scientists, Sergey and Nikita Zimov in the Russian Tundra and Jy Minh’s work in Hwang Woo-Suk’s Sooam Laboratories in South Korea to George Church’s lab work in Harvard. All these efforts are working towards resurrecting the woolly mammoth using DNA samples obtained from mammoths preserved in pristine conditions in the Arctic Tundra.
If that feels like Jurassic Park, it is, though the book explains why it is not exactly like Jurassic park, but sort of. It is Pleistocene Park – a concept that beat Jurassic Park by 2 years in conception.
If you are looking for a scientific explanation of techniques, and theory, this isn’t the book. The book is to be made into a movie, and is written as such: I can imagine the scenes leaping off the pages. Following the Russian scientists on a quest to resurrect life in the Arctic life makes a thrilling tale. Combining that with the race by Korean scientists to engineer and reverse engineer life, and scenes from a research laboratory down in Harvard makes for brilliant movie scenes. Only as the book assures you, it is not fictional. It is true. You will pause and think of ramifications, of the evil that can be wrought when powers like this fall into wrong hands, of political leaders with no qualifications dictating the genome factory.
Life from life, Minh thought, as he moved past the implantation table. Still, he couldn’t shake the chills he felt as he thought of those 3 dogs, lying supine, tongues hanging to the side around the breathing tubes, as the surgeons did their work. He chided himself for his own backward thinking: of course, futuristic science always seemed unnatural – until it became routine.
The discussion that evening over supper bleated over to the world’s most famous sheep, Dolly, who had been cloned in 1995. Sheep, Mammoths and Dogs make good cloning subjects for they do not yet touch the uncomfortable topic of human cloning.
http://www.businessinsider.com/sooam-biotechs-is-bringing-back-the-mammoth-2015-9
Human cloning, however, is a topic you can rely on authors to explore.
The thought provoking work by Kazuo Ishiguro, Never Let Me Go is worth a read in this context. The book talks of a future in which clones are generated from a master copy, and are raised separate from mainstream society, just so that they can function as ‘givers’ and ‘carers’ – a euphemism for organ donations. It is a heart rending read, as it centers around three young people, who have the same feelings of love, jealousy and friendship that ‘mainstream’ people do. Their art work is collected by a lady, who is trying to petition the state against this barbaric practice as Art shows the soul, and clearly the ‘spares’ have souls.

Human beings are tinkerers – we always have been. What have we in store this time?
- Is there a concept of the Soul that is separate from the engineered parts of cells, muscle, tissue and genes?
- Is Consciousness something that can be engineered?
- What role does our conscience play while tinkering consciously?
Related read: Of Dinosaurs, Genes & Aliens